Case Western Reserve scientists discovered that two common topical drugs appear to stimulate the production of oligodendrocytes to myelinate the central nervous system. The results of their investigation, published April 20, 2015 in Nature, give scientists cautious optimism that these drugs might effectively treat this disabling disease.

>> CLICK HERE to request more information or send comments to the research team

>> Read the CWRU press release
>> Read the press release from the NIH
>> Read the story on BBC News
>> Access the paper here

Congratulations to Angela Lager of the Tesar Lab on successfully defending her thesis "Cell Reprogramming Technologies for Treatment and Understanding of Genetic Disorders of Myelin". Best of luck to Dr. Lager as she moves on to a postdoc at the University of Wisconsin-Madison!

The International Society for Stem Cell Research (ISSCR) has named Paul Tesar Ph.D. of Case Western Reserve University the Outstanding Young Investigator for 2015. The award “recognizes the exceptional achievements of an investigator in the early part of his or her independent career in stem cell research who will be honored with the award at the ISSCR Annual Meeting in Stockholm, Sweden in June 2015.”

Dr. Tesar joins the ranks of previous winners Valentina Greco (Yale University), Marius Wernig (Stanford University), Cédric Blanpain (Université Libre De Bruxelles), Robert Blelloch (University of California, San Francisco), Joanna Wysocka (Stanford University) and Konrad Hochedlinger (Harvard University). The award reflects not only the caliber of Dr. Tesar’s work, but also the caliber of the stem cell community in Cleveland, Ohio.

Check out our newest publication in Cell Stem Cell on the discovery of "Seed" Enhancers and their role in pluripotent stem cells!

The finding stemmed from a synergy between the Tesar Laboratory's expertise in embryonic and epiblast stem cells and the genomics expertise of the Scacheri Laboratory. Both laboratories are part of the Genetics and Genome Sciences Department of Case Western Reserve University, Cleveland Ohio.

Congratulations to co-first authors Daniel Factor and Olivia Corradin!

Click Here for the press release.

Click Here for the article.

Cleveland area philanthropists Dr. Donald and Ruth Weber Goodman had a historic commitment to Research and Case Western Reserve University. Their outstanding generosity has supported education and research programs at the schools of medicine and dental medicine. Furthermore they have established two professorships, one of which was awarded to Paul Tesar.

Paul Tesar and the Tesar Lab sincerely thank the Goodman family for their support of our research and continued support of Case Western Reserve University!