Congrats to Zach who matched at Johns Hopkins in their Pediatric Genetic Medicine Residency Program!

Paul Tesar is selected as a member of the Provost's strategic planning committee. The "Thinkers" will identify and assess strategic choices for Case Western Reserve's future.

SOURCE Symposium and Poster Session is where CWRU undergraduates present their research and creative projects. Congratulations to Lucille for winning first place in Life Sciences for her poster, “Investigating the Mechanisms of Oligodendrocyte Damage in Hypoxia-Induced White Matter Injury.”

Our latest work has been published in Nature Communications "Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells". Congratulations to Angela Lager and the entire team! The work demonstrates a highly efficient method for generating oligodendrocytes and their progenitors from mouse ES and iPS cells providing a rapid platform for genotype–phenotype interrogation in oligodendrocytes.

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Our latest work on Pelizaeus-Merzbacher disease has been published in Stem Cell Reports. Congratulations to Matthew Elitt and the entire team for their efforts. Their work demonstrates the power of stem cell biology to uncover new pathological phases in this pediatric disease. These findings will be critical for the development of comprehensive therapies for patients.

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Our latest paper is out today in the journal Nature Methods. Congratulations to Mayur Madhavan, Zach Nevin, and the entire team on developing a method to generate human brain tissue in the laboratory from any patient. These “oligocortical spheroids” now include oligodendrocytes allowing us to study human myelin development and disease in the lab for the first time.

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We are proud to have collaborated with the Drew Adams lab on an exciting study published today in the journal Nature. The study defined a unifying mechanism by which small molecules stimulate the generation of new oligodendrocytes and enhance remyelination. This discovery will accelerate efforts to develop safe and effective medicines for patients with MS and other myelin disorders.

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