Our latest paper is out today in the journal Nature Methods. Congratulations to Mayur Madhavan, Zach Nevin, and the entire team on developing a method to generate human brain tissue in the laboratory from any patient. These “oligocortical spheroids” now include oligodendrocytes allowing us to study human myelin development and disease in the lab for the first time.

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We are proud to have collaborated with the Drew Adams lab on an exciting study published today in the journal Nature. The study defined a unifying mechanism by which small molecules stimulate the generation of new oligodendrocytes and enhance remyelination. This discovery will accelerate efforts to develop safe and effective medicines for patients with MS and other myelin disorders.

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Paul Tesar was selected as one of two recipients of the 2018 John S. Diekhoff Award for Mentoring. The annual award is presented to two faculty members who epitomize what it means to teach graduate students: to connect them with experts in their discipline, engage them academically in a forthright and collegial manner, and actively promote their professional development. One student award nominator wrote, “I want to be Paul when I become a faculty member myself, and it just isn’t his science … but his personal life and ability to balance the two…He is as good a mentor as he is a scientist.”

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Congrats to Tyler who recently started as a Clinical Pathology Resident at Massachusetts General Hospital. Tyler received his MD and PhD through Case’s MSTP program and plans to continue his research on glioblastoma in Boston.

CWRU hosts an annual research competition for all Case undergraduates who have conducted research, which is biologically related. This year, Lili was selected as a finalist to give an oral presentation and won! Congrats Lili!

Provost Summer Undergraduate Research Grant (PSURG) is a full-time summer program that supports undergraduate CWRU students. Sam’s project deals with the characterization of Astrocytes, cells integral for the function of the Central Nervous System. Specifically, he is focused on the role that dysfunctional astrocytes play in Vanishing White Matter Disease, a devastating genetic disorder that destroys the white matter of the brain and causes neurological symptoms. Congrats Sam!

Lucille was selected as one of two undergraduate students in the inaugural class of Beckman Scholars at CWRU. The prestigious undergraduate research grant and extensive mentorship was awarded for her research titled, “Investigating Methods and Mechanisms of Oligodendrocyte Restoration in Hypoxia-Induced White Matter Injury.”

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