News

Discovery of Induced-Oligodendrocyte Progenitors holds great promise for Medicine

Oligodendrocytes are the cell-type responsible for myelinating neurons of the brain. In myelin diseases, such as Multiple Sclerosis and Cerebral Palsy, oligodendrocytes are destroyed causing severe disability in patients. Researchers are desperate to understand disease pathology and also to develop cell transplantation therapies. However efforts have been largely hindered by limited access to oligodendrocytes.

The Tesar Lab has unlocked the potential to produce oligodendrocyte progenitors through a novel technique. This technique, published in Nature Biotechnology, involves directly converting fibroblasts into oligodendrocyte progenitors.

Tesar Lab Graduate Student Zachary Nevin Awarded Project Grant from the PMD Foundation

The PMD Foundation is an organization focused on serving those affected with Pelizaeus Merzbacher Disease (PMD). Click Here for more information.

MD/PhD student Zachary Nevin was awarded the James Y Garbern Research Project Grant to conduct his work on PMD patient specific induced pluripotent stem cell lines. Click Here for the press release.

Are Online Classes the Wave of the Future?

The internet has provided a conduit for the world to be connected. Pictures, videos, feelings, and ideas can be communicated instantly with the touch of a screen.

With these means of communication emerging at supersonic pace and reaching unprecedented numbers of people, it is up to us to ensure that the content we distribute is of high quality and improves our lives.

Paul Tesar was recently filmed in a RENEW online course. The RENEW initiative is focused on collecting videotaped courses and sharing these courses with students all over the world. Paul was elated to be part of the initiative by sharing his session on reprogramming technology. Paul hopes to make contagious his passion for science and inspire the next generation of scientists.

Tesar Lab Graduate Student Angela Lager Awarded Training Fellowship

Congratulations to our own Angela Lager for being awarded an Individual Training Fellowship supported by the National Institute of Neurological Disorders and Stroke.

The purpose of this individual predoctoral research training fellowship is to provide support for promising doctoral candidates who will be performing dissertation research and training in scientific health-related fields relevant to the missions of the participating NIH Institutes and Centers (ICs) during the tenure of the award.

Paul Tesar visits the University of Edinburgh in Scotland

Paul Tesar was invited to speak at the MRC Centre for Regenerative Medicine at the University of Edinburgh in Scotland on January 23rd 2013. His talk was titled "Stem cell and reprogramming technologies for the study and treatment of myelin diseases". Paul is grateful to his colleagues and friends at the University of Edinburgh and hopes to return in the near future.

Tesar/Scacheri Lab Retreat 2012

The Tesar and Scacheri Labs traveled to a lodge in Logan Ohio for their First Annual Lab Retreat. The event consisted of a 'Lab Olympics' competition, teambuilding exercises, talking science, having fun, and eating lots of great food! Thanks to everyone, especially Angela Lager, Olivia Corradin, and Cynthia Bartels, for making the event a great success.

Congratulations to Angela Lager for her award winning work

Tesar Lab graduate student Angela Lager has presented her work "Direct Reprogramming of Mouse Fibroblasts to Oligodendrocyte Progenitor Cells" and won awards at these symposia:
CWRU 25th Annual Biomedical Graduate Student Symposium, Vance Lemmon Award
CWRU 1st Annual Graduate Student Research Symposium, Best Poster

Congratulations to Angela!

Congratulations to Bobby Karl for winning a CWRU Cell and Molecular Biology Training Grant

Tesar Lab graduate student Bobby Karl was awarded the CWRU Cell and Molecular Biology Training Grant for his work on cellular reprogramming to the oligodendrocyte lineage with modified mRNA. Congratulations to Bobby!

Tesar Lab Graduate Student Dan Factor attends conference in China

Tesar Lab graduate student Dan Factor attended and presented his work "Epigenomic analysis identifies cell type specific regulatory elements of distinct pluripotent states" at a conference in China. The conference was Cold Spring Harbor Asia: Epigenetics, Chromatin & Transcription and held in Suzhou Dushu Lake China.

Advance in Human Cloning: Paul Tesar and Insoo Hyun Comment in Nature

See the Correspondence in Nature by Paul Tesar and Insoo Hyun.
Work done in labs part of the New York Stem Cell Foundation uncovered that pluripotent stem cells could be made by fusing somatic cells and human oocytes. Tesar and Hyun discuss the scientific impact and ethical implications.
Click Here for the link.

Pages

Subscribe to News