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Tesar Lab Graduate Student Daniel Factor Wins Award at Cell Symposium

Congratulations to Tesar Lab Graduate Student Daniel Factor who recently attended the 2014 Cell Symposium on Transcriptional Regulation in Development in Chicago. At the conference, Factor was awarded the Joy Cappel 2014 Young Investigator Award for his work recently published in Cell Stem Cell (Link Here). Factor also received a Poster Award for presenting his work at the conference.

Discovery of "Seed" Enhancers

Check out our newest publication in Cell Stem Cell on the discovery of "Seed" Enhancers and their role in pluripotent stem cells!

The finding stemmed from a synergy between the Tesar Laboratory's expertise in embryonic and epiblast stem cells and the genomics expertise of the Scacheri Laboratory. Both laboratories are part of the Genetics and Genome Sciences Department of Case Western Reserve University, Cleveland Ohio.

Congratulations to co-first authors Daniel Factor and Olivia Corradin!

Click Here for the press release.

Click Here for the article.

Paul Tesar awarded the Dr. Donald and Ruth Weber Goodman Professor of Innovative Therapeutics

Cleveland area philanthropists Dr. Donald and Ruth Weber Goodman had a historic commitment to Research and Case Western Reserve University. Their outstanding generosity has supported education and research programs at the schools of medicine and dental medicine. Furthermore they have established two professorships, one of which was awarded to Paul Tesar.

Paul Tesar and the Tesar Lab sincerely thank the Goodman family for their support of our research and continued support of Case Western Reserve University!

Tesar Lab awarded new grant from NINDS to advance novel therapeutics for multiple sclerosis

The Tesar Lab was recently awarded a grant from the National Institute of Neurological Disorders and Stroke to advance therapeutics for multiple sclerosis. The Tesar Lab's expertise in stem cell biology and high throughput screening provides a unique opportunity to discover innovative therapeutics that could halt devastating diseases.

Discovery of Induced-Oligodendrocyte Progenitors holds great promise for Medicine

Oligodendrocytes are the cell-type responsible for myelinating neurons of the brain. In myelin diseases, such as Multiple Sclerosis and Cerebral Palsy, oligodendrocytes are destroyed causing severe disability in patients. Researchers are desperate to understand disease pathology and also to develop cell transplantation therapies. However efforts have been largely hindered by limited access to oligodendrocytes.

The Tesar Lab has unlocked the potential to produce oligodendrocyte progenitors through a novel technique. This technique, published in Nature Biotechnology, involves directly converting fibroblasts into oligodendrocyte progenitors.

Are Online Classes the Wave of the Future?

The internet has provided a conduit for the world to be connected. Pictures, videos, feelings, and ideas can be communicated instantly with the touch of a screen.

With these means of communication emerging at supersonic pace and reaching unprecedented numbers of people, it is up to us to ensure that the content we distribute is of high quality and improves our lives.

Paul Tesar was recently filmed in a RENEW online course. The RENEW initiative is focused on collecting videotaped courses and sharing these courses with students all over the world. Paul was elated to be part of the initiative by sharing his session on reprogramming technology. Paul hopes to make contagious his passion for science and inspire the next generation of scientists.

Tesar Lab Graduate Student Angela Lager Awarded Training Fellowship

Congratulations to our own Angela Lager for being awarded an Individual Training Fellowship supported by the National Institute of Neurological Disorders and Stroke.

The purpose of this individual predoctoral research training fellowship is to provide support for promising doctoral candidates who will be performing dissertation research and training in scientific health-related fields relevant to the missions of the participating NIH Institutes and Centers (ICs) during the tenure of the award.

Tesar Lab Graduate Student Zachary Nevin Awarded Project Grant from the PMD Foundation

The PMD Foundation is an organization focused on serving those affected with Pelizaeus Merzbacher Disease (PMD). Click Here for more information.

MD/PhD student Zachary Nevin was awarded the James Y Garbern Research Project Grant to conduct his work on PMD patient specific induced pluripotent stem cell lines. Click Here for the press release.

Paul Tesar visits the University of Edinburgh in Scotland

Paul Tesar was invited to speak at the MRC Centre for Regenerative Medicine at the University of Edinburgh in Scotland on January 23rd 2013. His talk was titled "Stem cell and reprogramming technologies for the study and treatment of myelin diseases". Paul is grateful to his colleagues and friends at the University of Edinburgh and hopes to return in the near future.

Tesar/Scacheri Lab Retreat 2012

The Tesar and Scacheri Labs traveled to a lodge in Logan Ohio for their First Annual Lab Retreat. The event consisted of a 'Lab Olympics' competition, teambuilding exercises, talking science, having fun, and eating lots of great food! Thanks to everyone, especially Angela Lager, Olivia Corradin, and Cynthia Bartels, for making the event a great success.

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